Area

Proteomics



This area consists of three units: Mass Spectrometry (MS), Reverse Phase microArray (RPPA) and surface plasmon resonance (Biacore).

Mass spectrometry is applicable to semi-purified proteins to identify and characterize post-translational modifications and adducts, as well as to the qualitative and quantitative study of complex mixtures, sub-cellullar and total proteomes, biomarker research and protein complex analysis. The unit also makes use of expertise in the preparation of biological samples and bioinformatic data analysis.

The RPPA analysis studies the levels of signal transduction activity. Immunostaining, using more than 400 validated antibodies, allows automated semi-quantitative measurement of a large number of samples.

The Surface Plasmon Resonance (SPR - Biacore) technique allows studying the interactions between a ligand and putative substates anchored onto a gold-chip, in a pM range of the bulk, with a very high sensibility (few pg/mm²).


Contact: Serena Camerini
+39 06 4990 3164
Fax +39 06 4990 2040