https://corefacilities.iss.it/dw/ 2026-05-18T21:33:02+02:00 https://corefacilities.iss.it/dw/ https://corefacilities.iss.it/dw/lib/tpl/bootstrap3gscf/images/favicon.ico text/html 2019-06-13T16:02:02+02:00 https://corefacilities.iss.it/dw/doku.php?id=en:aree:microscopia:elettronica:contrasto_negativo:galleria Electron Microscopy Unit - Techniques Negative staining Gallery ⇐ Back text/html 2019-06-13T15:56:41+02:00 https://corefacilities.iss.it/dw/doku.php?id=en:aree:microscopia:elettronica:contrasto_negativo:start Electron Microscopy Unit - Techniques Negative staining Negative staining is a powerful TEM method for studying particulate samples characterized by very law dimensions such as biological macromolecules, purified cellular organelles, exosomes, viruses and bacteria. A high atomic weight element solution is used to create an electronic contrast on samples deposed on carbon coated TEM grids. The biological structures repulse the high atomic weight ions of the staining solution depositing around t…