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en:aree:proteomica:start [2022/02/24 18:59]
Gianluca Frustagli Added new "Biacore Unit".
en:aree:proteomica:start [2022/10/17 15:36]
Gianluca Frustagli Added NTA unit.
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 ====== Proteomics ====== ====== Proteomics ======
  
-<WRAP bigger button centeralign>​[[en:​aree:​proteomica:​ms:​|MS Unit]] [[en:​aree:​proteomica:​rppa:​|RPPA Unit]] [[en:aree:proteomica:biacore:|Biacore Unit]]</​WRAP>​ \\ \\+<WRAP bigger button centeralign>​[[en:​aree:​proteomica:​ms:​|MS Unit]] [[en:​aree:​proteomica:​rppa:​|RPPA Unit]] [[en:​aree:​proteomica:​biacore:​|Biacore ​Unit]] [[en:​aree:​proteomica:​nta:​|NTA ​Unit]]</​WRAP>​ \\ \\
  
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-{{:​aree:​proteomica:​proteomica.png?​300 |}} This area consists of three units: **Mass Spectrometry ([[:​aree:​proteomica:​ms:​|MS]])**,​ **Reverse Phase microArray ([[:​aree:​proteomica:​rppa:​|RPPA]])** and **surface plasmon resonance ([[:aree:proteomica:biacore:|Biacore]])**.+{{:​aree:​proteomica:​proteomica.png?​300 |}} This area consists of three units: **Mass Spectrometry ([[:​aree:​proteomica:​ms:​|MS]])**,​ **Reverse Phase microArray ([[:​aree:​proteomica:​rppa:​|RPPA]])** and **surface plasmon resonance ([[en:​aree:​proteomica:​biacore:​|Biacore]])**.
  
 Mass spectrometry is applicable to semi-purified proteins to identify and characterize post-translational modifications and adducts, as well as to the qualitative and quantitative study of complex mixtures, sub-cellullar and total proteomes, biomarker research and protein complex analysis. The unit also makes use of expertise in the preparation of biological samples and bioinformatic data analysis. Mass spectrometry is applicable to semi-purified proteins to identify and characterize post-translational modifications and adducts, as well as to the qualitative and quantitative study of complex mixtures, sub-cellullar and total proteomes, biomarker research and protein complex analysis. The unit also makes use of expertise in the preparation of biological samples and bioinformatic data analysis.
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 The Surface Plasmon Resonance (SPR - Biacore) technique allows studying the interactions between a ligand and putative substates anchored onto a gold-chip, in a pM range of the bulk, with a very high sensibility (few pg/mm²). The Surface Plasmon Resonance (SPR - Biacore) technique allows studying the interactions between a ligand and putative substates anchored onto a gold-chip, in a pM range of the bulk, with a very high sensibility (few pg/mm²).
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 +The Nanoparticles Tracking Analysis (NTA) is a method for measuring the size and concentration of particles with a diameter of 10-2000 nm in suspension which therefore finds multiple domains of application.
  
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