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en:aree:nmr:start [2020/01/28 17:57] Gianluca Frustagli |
en:aree:nmr:start [2023/02/16 01:50] Gianluca Frustagli Update for new instrumentation. |
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| - | **Area** | + | **NMR & MRI Area** |
| <html><h2 style="text-align: center;">High resolution NMR and Preclinic MRI</h2></html> | <html><h2 style="text-align: center;">High resolution NMR and Preclinic MRI</h2></html> | ||
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| + | The NMR area is equipped with: | ||
| - | * The **[[en:aree:nmr:hrnmr:|High-Resolution Nuclear Magnetic Resonance (HR-NMR) Unit]]** is equipped with a spectrometer operating at 9.4 T for metabolism and metabolomics studies in cells, biological fluids and tissues. In particular, the HR-NMR Unit provides services for identification and detection of various classes of small molecules, metabolites, and lipids in mammalian and microbial cells; targeted and untargeted analyses and quantification of various classes of molecules ranging from small metabolites to lipids in a variety of biological matrices. | + | * a high resolution spectrometer operating at 14 T for metabolism and metabolomics studies in cells, biological fluids and tissues (high resolution NMR units); |
| + | * an MR system for in vivo imaging and spectroscopy for small animals operating at 7 T for morphological, metabolic and functional imaging studies (in-vivo MRI unit); | ||
| - | * The **[[en:aree:nmr:mri:|preclinic MRI Unit]]** is equipped with a system for imaging, operating at 4.7 T for morphological, molecular and functional imaging and spectroscopy studies on rodents in vivo. Experience in neurodevelopmental and neurodegenerative pathology as well as several types of cancers in animal models to identify through quantitative protocols early biomarker of pathology progression or response to therapy. | + | The area makes use of pre-clinical research skills in oncology, neuroscience, aging and metabolic diseases. |
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| - | <wrap hi>We are in the course of acquiring new state of the art instrumentations (a 7 T system for in vivo MRI/MRS analyses and a 14 T spectrometer for HR-NMR).</wrap> | + | |
| > Contact: [[rossella.canese@iss.it|Rossella Canese]] | > Contact: [[rossella.canese@iss.it|Rossella Canese]] | ||
